INSTRUCTIONAL UNITS


Biodiversity

Evolution

Biochemistry

Cell Biology

Energy and Metabolism (Part 1)

Energy and Metabolism (Part 2)

Classical Genetics

Molecular Genetics (Basic)

Molecular Genetics (Advanced)

Immunology and Homeostasis

Chemical and Neural Signaling

Animal Reproduction and Development

Plant Biology

Ecology

Neuroscience




Molecular Genetics
(Chapters 16 & 17)

With the discovery of the structure of DNA in 1953 by James Watson and Francis Crick a new era of genetics was ushered in- the era of molecular genetics. This unit explores the molecular basis of the gene and in particular how the DNA code is translated into a protein.

Lecture

Chapter 16 Lecture 1 (print) (audio 25:08) (MIT video version of my lectures 1 & 2- Excellent Resource!)

Chapter 16 Lecture 2 (print) (audio 13:29)

"Race for the Double Helix" (movie)

Chapter 16 Lecture 3 (print) (audio 27:15)
DNA Replication: Animations
Go to -> 16.2 Overview of DNA Replication & 16.3 A Closer Look at DNA Replication
DNA Replication: Basic Details
DNA Replication: Advanced Details

Chapter 16 Lecture 4 (print) (audio 16:09)

Chapter 17 Lecture 1: What Does DNA do? (print) (audio 23:35)

Chapter 17 Lecture 2: Protein Synthesis and Cooking Analogy (print) (audio 40:18)

Chapter 17 Lecture 3: Transcription (print) (audio- see previous lecture)

Chapter 17 Lecture 4: RNA Processing in Eukaryotes
(print) (audio 22:13)

Chapter 17 Lecture 5: Translation (print) (audio18:21)

Chapter 17 Lecture 6: Mutations (print) (audio 17:17)

Chapter 17 Lecture 7: Wrap up (print) (audio 8:57)


Homework

Chapter 16 Free Response Questions

Chapter 17 Free Response Questions

Decoding the Genetic Code HW

Decoding the Genetic Code HW (Key)

Meselson-Stahl Experiment Activity

Animation of the Meselson-Stahl Experiment (DNA From the Beginning)

Animation of the Meselson-Stahl Experiment (From a textbook publisher)

Matthew Meselson Explains the Experiment (13:11)

Molecular Wars Reading

Can A Jellyfish Unlock the Secrets of Immortality?

From Bacteria to Us (NY Times, January 3, 2006)

The Rest of the Genome (NY Times, November 10, 2008)

Lab

DNA Model Activity

DNA Model Activity "How to" Video

tRNA Activity

Insulin mRNA to Protein Lab

Test Prep

Chapter 16 Quiz #1 Hints

Chapter 16 Quiz #2 Hints

Chapter 16 Test Hints

Chapter 17 Quiz Hints #1

Chapter 17 Quiz Hints #2

Chapter 17 Test Hints

Web Resources

GenEd Website

Web Based Resources to Help You Learn Molecular Genetics

Genomes (free online book)

The New Genetics (from the National Institute of General Medical Sciences)

RNAi Fact Sheet

Remarkable RNAs

Essentials of Genetics- Scitable by Nature Education

Basic Genetics Resources- Nature Journal

Cancer- Scitable by Nature Education

Advanced Genetics Resources- Nature Journal

The Basics of DNA

Using Model Organisms to Study Health and Disease

How Model Organisms Advance Science

pen University Genetics

Practice Doing Translation


Introduction to Genetic Analysis (Excellent Resource!)

Are Telomere's the Cause of Aging? (University of Utah)

Uracil created in a NASA lab

Genetics Home Reference

Online Mendelian Inheritance in Man

Personal Genome Education Project